Cargando…

Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells

The antibody-dependent cellular cytotoxicity (ADCC) of natural killer (NK) cells is assumed to contribute to the clinical efficacy of monoclonal antibodies (mAbs) in chronic lymphocytic leukemia (CLL) and other hematopoietic malignancies of B cell origin. We sought to determine whether reactive oxyg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Werlenius, Olle, Aurelius, Johan, Hallner, Alexander, Akhiani, Ali A., Simpanen, Maria, Martner, Anna, Andersson, Per-Ola, Hellstrand, Kristoffer, Thorén, Fredrik B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077995/ https://www.ncbi.nlm.nih.gov/pubmed/27097113 http://dx.doi.org/10.18632/oncotarget.8769

Ejemplares similares

Role of the ERK Pathway for Oxidant-Induced Parthanatos in Human Lymphocytes
por: Akhiani, Ali A., et al.
Publicado: (2014)

Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia
por: Martner, Anna, et al.
Publicado: (2015)

Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia
por: Bernson, E, et al.
Publicado: (2017)

NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance
por: Martner, Anna, et al.
Publicado: (2015)

Complete remission after the first cycle of induction chemotherapy determines the clinical efficacy of relapse‐preventive immunotherapy in acute myeloid leukaemia
por: Nilsson, Malin S., et al.
Publicado: (2019)

Immunotherapy with HDC/IL-2 may be clinically efficacious in acute myeloid leukemia of normal karyotype
por: Nilsson, Malin S., et al.
Publicado: (2019)

Impact of NK Cell Activating Receptor Gene Variants on Receptor Expression and Outcome of Immunotherapy in Acute Myeloid Leukemia
por: Hussein, Brwa Ali, et al.
Publicado: (2021)

Corrigendum: Impact of NK Cell Activating Receptor Gene Variants on Receptor Expression and Outcome of Immunotherapy in Acute Myeloid Leukemia
por: Hussein, Brwa Ali, et al.
Publicado: (2022)

Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia
por: Sander, Frida Ewald, et al.
Publicado: (2016)

NOX2 inhibition reduces oxidative stress and prolongs survival in murine KRAS-induced myeloproliferative disease
por: Aydin, Ebru, et al.
Publicado: (2018)

Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2
por: Kiffin, Roberta, et al.
Publicado: (2018)

HLA-B*44 and the Bw4-80T motif are associated with poor outcome of relapse-preventive immunotherapy in acute myeloid leukemia
por: Komic, Hana, et al.
Publicado: (2023)

Role of regulatory T cells in acute myeloid leukemia patients undergoing relapse-preventive immunotherapy
por: Sander, Frida Ewald, et al.
Publicado: (2017)

Impact of IL-1β and the IL-1R antagonist on relapse risk and survival in AML patients undergoing immunotherapy for remission maintenance
por: Grauers Wiktorin, Hanna, et al.
Publicado: (2021)

Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells
por: Wenger, Anna, et al.
Publicado: (2017)

NKG2A gene variant predicts outcome of immunotherapy in AML and modulates the repertoire and function of NK cells
por: Hussein, Brwa Ali, et al.
Publicado: (2023)

IFNL4 Genotypes Predict Clearance of RNA Viruses in Rwandan Children With Upper Respiratory Tract Infections
por: Rugwizangoga, Belson, et al.
Publicado: (2019)

NOX2 in autoimmunity, tumor growth and metastasis
por: Martner, Anna, et al.
Publicado: (2018)

Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells
por: Ghamlouch, Hussein, et al.
Publicado: (2015)

Role of Phosphoinositide 3-Kinase in Regulation of NOX-Derived Reactive Oxygen Species in Cancer
por: Akhiani, Ali A., et al.
Publicado: (2022)

Natural Killer Cell Mediated Antibody-Dependent Cellular Cytotoxicity in Tumor Immunotherapy with Therapeutic Antibodies
por: Seidel, Ursula J. E., et al.
Publicado: (2013)

Cytotoxicity of the CD3×CD20 bispecific antibody epcoritamab in CLL is increased by concurrent BTK or BCL-2 targeting
por: Mhibik, Maissa, et al.
Publicado: (2023)

NOX2-Derived Reactive Oxygen Species in Cancer
por: Grauers Wiktorin, Hanna, et al.
Publicado: (2020)

Cytotoxicity of cytokine-induced killer cells targeted by a bispecific antibody to gastric cancer cells
por: ZHANG, LIN, et al.
Publicado: (2013)

Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity
por: Bernard, Nicole F., et al.
Publicado: (2017)

The role of natural killer cells and antibody-dependent cell-mediated cytotoxicity during murine cytomegalovirus infection
Publicado: (1979)

Effect of chemotherapy on natural-killer activity and antibody-dependent cell-mediated cytotoxicity in carcinoma of the lung.
por: Saijo, N., et al.
Publicado: (1982)

Antibody‐dependent cellular cytotoxicity toward neuroblastoma enhanced by activated invariant natural killer T cells
por: Mise, Naoko, et al.
Publicado: (2016)

TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20(+) Antibody-Secreting Cells
por: Ghamlouch, Hussein, et al.
Publicado: (2014)

Vaccine-Induced Antibodies Mediate Higher Antibody-Dependent Cellular Cytotoxicity After Interleukin-15 Pretreatment of Natural Killer Effector Cells
por: Fisher, Leigh, et al.
Publicado: (2019)

Natural Killer Cells in Antibody Independent and Antibody Dependent HIV Control
por: Bernard, Nicole F., et al.
Publicado: (2022)

Sensitive Detection of the Natural Killer Cell-Mediated Cytotoxicity of Anti-CD20 Antibodies and Its Impairment by B-Cell Receptor Pathway Inhibitors
por: Hassenrück, Floyd, et al.
Publicado: (2018)

Low Incidence of Reinfection With Endemic Coronaviruses Diagnosed by Real-Time PCR
por: Ringlander, Johan, et al.
Publicado: (2020)

Influence of Cytokines on HIV-Specific Antibody-Dependent Cellular Cytotoxicity Activation Profile of Natural Killer Cells
por: Wren, Leia, et al.
Publicado: (2012)

Release of Esterase from Murine Lymphokine‐activated Killer Cells in Antibody‐dependent Cellular Cytotoxic Reaction
por: Kato, Kazunori, et al.
Publicado: (1991)

Synergistic Effects of Venetoclax and Daratumumab on Antibody-Dependent Cell-Mediated Natural Killer Cytotoxicity in Multiple Myeloma
por: Nakamura, Ayano, et al.
Publicado: (2021)

BTK inhibitors and anti-CD20 monoclonal antibodies for treatment-naïve elderly patients with CLL
por: Rogers, Andrew, et al.
Publicado: (2020)

Idelalisib improves CD37 antibody BI 836826 cytotoxicity against chemo-resistant /relapse-initiating CLL cells: a rationale for combination treatment
por: Betrian, S, et al.
Publicado: (2016)

Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibody
por: Ciszak, Lidia, et al.
Publicado: (2015)

Transient and durable T cell reactivity after COVID-19
por: Martner, Anna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5q67u6sa16405n55gidbesdik3