Cargando…

Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

INTRODUCTION: Intraoperative fluorescence imaging of the folate-receptor alpha (FRα) could support completeness of resection in cancer surgery. Feasibility of EC17, a FRα-targeting agent that fluoresces at 500nm, was demonstrated in a limited series of ovarian cancer patients. Our objective was to e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tummers, Quirijn R.J.G., Hoogstins, Charlotte E.S., Gaarenstroom, Katja N., de Kroon, Cor D., van Poelgeest, Mariette I.E., Vuyk, Jaap, Bosse, Tjalling, Smit, Vincent T.H.B.M, van de Velde, Cornelis J.H., Cohen, Adam F., Low, Philip S., Burggraaf, Jacobus, Vahrmeijer, Alexander L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078003/ https://www.ncbi.nlm.nih.gov/pubmed/27014973 http://dx.doi.org/10.18632/oncotarget.8282

Ejemplares similares

Folate receptor-α targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study
por: Boogerd, Leonora S.F., et al.
Publicado: (2017)

Integrin αvβ6 as a Target for Tumor-Specific Imaging of Vulvar Squamous Cell Carcinoma and Adjacent Premalignant Lesions
por: Huisman, Bertine W., et al.
Publicado: (2021)

The Value of Intraoperative Near-Infrared Fluorescence Imaging Based on Enhanced Permeability and Retention of Indocyanine Green: Feasibility and False-Positives in Ovarian Cancer
por: Tummers, Quirijn R. J. G., et al.
Publicado: (2015)

Intraoperative near-infrared fluorescence imaging of a paraganglioma using methylene blue: A case report
por: Tummers, Quirijn R.J.G., et al.
Publicado: (2014)

Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients
por: Boogerd, Leonora S. F., et al.
Publicado: (2016)

Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer
por: van Esterik, Manouk, et al.
Publicado: (2017)

In Search for Optimal Targets for Intraoperative Fluorescence Imaging of Peritoneal Metastasis From Colorectal Cancer
por: Hoogstins, Charlotte ES, et al.
Publicado: (2017)

Novel Molecular Targets for Tumor-Specific Imaging of Epithelial Ovarian Cancer Metastases
por: de Muynck, Lysanne D. A. N., et al.
Publicado: (2020)

Correlation Between Preoperative Serum Carcinoembryonic Antigen Levels and Expression on Pancreatic and Rectal Cancer Tissue
por: Boogerd, LSF, et al.
Publicado: (2017)

The RAD51-FFPE Test; Calibration of a Functional Homologous Recombination Deficiency Test on Diagnostic Endometrial and Ovarian Tumor Blocks
por: van Wijk, Lise M., et al.
Publicado: (2021)

MGL Ligand Expression Is Correlated to Lower Survival and Distant Metastasis in Cervical Squamous Cell and Adenosquamous Carcinoma
por: Sahasrabudhe, Neha M., et al.
Publicado: (2019)

uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery
por: Boonstra, Martin C., et al.
Publicado: (2015)

Performance of the pattern‐based interpretation of p53 immunohistochemistry as a surrogate for TP53 mutations in vulvar squamous cell carcinoma
por: Kortekaas, Kim E, et al.
Publicado: (2020)

Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent
por: Hoogstins, Charlotte E. S., et al.
Publicado: (2018)

Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic
por: Reddy, Joseph A., et al.
Publicado: (2018)

High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status
por: Kortekaas, Kim E., et al.
Publicado: (2019)

Intraoperative detection of the remnant cystic duct during robot-assisted surgery using near-infrared fluorescence imaging: a case report
por: van Manen, Labrinus, et al.
Publicado: (2019)

The Paget Trial: A Multicenter, Observational Cohort Intervention Study for the Clinical Efficacy, Safety, and Immunological Response of Topical 5% Imiquimod Cream for Vulvar Paget Disease
por: van der Linden, Michelle, et al.
Publicado: (2017)

Primary Malignant Lymphoma of the Uterus: A Case Report and Review of the Literature
por: Samama, Margriet, et al.
Publicado: (2011)

Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer
por: Kortekaas, Kim E., et al.
Publicado: (2020)

Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics
por: in ’t Veld, Aliede E., et al.
Publicado: (2022)

Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays
por: in ’t Veld, Aliede E., et al.
Publicado: (2023)

Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent
por: Reddy, Joseph A., et al.
Publicado: (2020)

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer
por: Dijkgraaf, Eveline M., et al.
Publicado: (2015)

Antitumor activity of folate-targeted, paclitaxelloaded polymeric micelles on a human esophageal EC9706 cancer cell line
por: Wu, Wenbin, et al.
Publicado: (2012)

Quantitative dynamic near-infrared fluorescence imaging using indocyanine green for analysis of bowel perfusion after mesenteric resection
por: Meijer, Ruben P. J., et al.
Publicado: (2021)

Synergy of therapeutic vaccination against HPV16 oncogenic proteins and standard chemotherapeutics
por: Melief, Cornelis J, et al.
Publicado: (2014)

POLE proofreading mutation, immune response and prognosis in endometrial cancer
por: van Gool, Inge C., et al.
Publicado: (2015)

Deploy Containers on AWS: With EC2, ECS, and EKS
por: Ifrah, Shimon
Publicado: (2019)

Erratum to: Prospective Clinical and Pharmacological Evaluation of the Delcath System’s Second-Generation (GEN2) Hemofiltration System in Patients Undergoing Percutaneous Hepatic Perfusion with Melphalan
por: de Leede, Eleonora M., et al.
Publicado: (2017)

Prospective Clinical and Pharmacological Evaluation of the Delcath System’s Second-Generation (GEN2) Hemofiltration System in Patients Undergoing Percutaneous Hepatic Perfusion with Melphalan
por: de Leede, Eleonora M., et al.
Publicado: (2017)

Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer
por: de Valk, Kim S., et al.
Publicado: (2020)

Multimodal image-guided surgery of HER2-positive breast cancer using [(111)In]In-DTPA-trastuzumab-IRDye800CW in an orthotopic breast tumor model
por: Deken, Marion M., et al.
Publicado: (2019)

Relations with the EC
Publicado: (1992)

Prognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas
por: Trietsch, Marjolijn D., et al.
Publicado: (2016)

Safety of monosodium salt of l‐5‐methyltetrahydrofolic acid as a novel food pursuant to Regulation (EU) 2015/2283 and the bioavailability of folate from this source in the context of Directive 2002/46/EC, Regulation (EU) No 609/2013 and Regulation (EC) No 1925/2006
por: Turck, Dominique, et al.
Publicado: (2023)

The combined effect of Bassa 50EC and Vitashield 40EC on the brain acetylcholinesterase activity in climbing perch (Anabas testudineus)
por: Tam, Nguyen Thanh, et al.
Publicado: (2018)

Effectiveness of 3 Polyherbal Formulations (EcXaPu, EcXa, and EcPu) on the Management of Oxidative Stress and Hyperglycemia
por: Essola, Nadine Ndoe, et al.
Publicado: (2022)

Possible role of the Ec peptide of IGF-1Ec in cartilage repair
por: Armakolas, Nikolaos, et al.
Publicado: (2016)

Depression, antidepressants and fall risk: therapeutic dilemmas—a clinical review
por: van Poelgeest, E. P., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_012rh9oujk7n946oej847m8728