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Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

Considerable evidence from both clinical and experimental studies suggests that androgen receptor variants, particularly androgen receptor variant 7 (AR-V7), are critical in the induction of resistance to enzalutamide and abiraterone. In this study, we investigated the role of AR-V7 in the cross-res...

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Detalles Bibliográficos
Autores principales: Liu, Chengfei, Armstrong, Cameron, Zhu, Yezi, Lou, Wei, Gao, Allen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078008/
https://www.ncbi.nlm.nih.gov/pubmed/27049719
http://dx.doi.org/10.18632/oncotarget.8493