Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

Metabolic changes are associated with cancer, but whether they are just bystander effects of deregulated oncogenic signaling pathways or characterize early phases of tumorigenesis remains unclear. Here we show in a rat model of hepatocarcinogenesis that early preneoplastic foci and nodules that prog...

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Detalles Bibliográficos
Autores principales: Kowalik, Marta Anna, Guzzo, Giulia, Morandi, Andrea, Perra, Andrea, Menegon, Silvia, Masgras, Ionica, Trevisan, Elena, Angioni, Maria Maddalena, Fornari, Francesca, Quagliata, Luca, Ledda-Columbano, Giovanna Maria, Gramantieri, Laura, Terracciano, Luigi, Giordano, Silvia, Chiarugi, Paola, Rasola, Andrea, Columbano, Amedeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078020/
https://www.ncbi.nlm.nih.gov/pubmed/27070090
http://dx.doi.org/10.18632/oncotarget.8632

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