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Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting

The therapeutic efficacy of most anti-cancer drugs depends on their apoptosis-inducing abilities. Previously, we showed that a peptide containing the mitochondrial targeting domain (MTD) found in Noxa, a BH-3 only protein of Bcl-2 family, induces necrosis. Here, a fusion peptide of neuropilin-1 (NRP...

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Detalles Bibliográficos
Autores principales:	Kim, Ji-Young, Han, Ji-Hae, Park, Geon, Seo, Young-Woo, Yun, Cheol-Won, Lee, Byung-Chul, Bae, Jeehyeon, Moon, Ae Ran, Kim, Tae-Hyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078025/ https://www.ncbi.nlm.nih.gov/pubmed/27083053 http://dx.doi.org/10.18632/oncotarget.8719

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