Cargando…

Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5

MiRNAs in the circulation have been demonstrated to be a type of signaling molecule involved in intercellular communication but little is known about their role in regulating radiosensitivity. This study aims to investigate the effects of extracellular miRNAs induced by ionizing radiation (IR) on ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Dexiao, Xu, Jinping, Wang, Juan, Pan, Yan, Fu, Jiamei, Bai, Yang, Zhang, Jianghong, Shao, Chunlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078045/ https://www.ncbi.nlm.nih.gov/pubmed/27129166 http://dx.doi.org/10.18632/oncotarget.9017

Ejemplares similares

LncRNA CASC19 Enhances the Radioresistance of Nasopharyngeal Carcinoma by Regulating the miR-340-3p/FKBP5 Axis
por: Liu, Hongxia, et al.
Publicado: (2023)

Expression and Diagnostic Value of miR-497 and miR-1246 in Hepatocellular Carcinoma
por: Chen, Shuying, et al.
Publicado: (2021)

A Review on the Role of miR-1246 in the Pathoetiology of Different Cancers
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

Serum miR-1290 and miR-1246 as Potential Diagnostic Biomarkers of Human Pancreatic Cancer
por: Wei, Jia, et al.
Publicado: (2020)

CD81 Enhances Radioresistance of Glioblastoma by Promoting Nuclear Translocation of Rad51
por: Zheng, Wang, et al.
Publicado: (2021)

Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer
por: Xu, Yi-Fan, et al.
Publicado: (2017)

GDF15 Contributes to Radioresistance by Mediating the EMT and Stemness of Breast Cancer Cells
por: Zhao, Xinrui, et al.
Publicado: (2022)

The Diagnostic Power of Circulating miR-1246 in Screening Cancer: An Updated Meta-analysis
por: Huynh, Khanh Quang, et al.
Publicado: (2023)

Usefulness of serum miR-1246/miR-106b ratio in patients with esophageal squamous cell carcinoma
por: Hoshino, Isamu, et al.
Publicado: (2020)

lncRNA CASC19 Contributes to Radioresistance of Nasopharyngeal Carcinoma by Promoting Autophagy via AMPK-mTOR Pathway
por: Liu, Hongxia, et al.
Publicado: (2021)

miR-1246 in tumor extracellular vesicles promotes metastasis via increased tumor cell adhesion and endothelial cell barrier destruction
por: Morimoto, Masahiro, et al.
Publicado: (2023)

Exosomal protein angiopoietin-like 4 mediated radioresistance of lung cancer by inhibiting ferroptosis under hypoxic microenvironment
por: Zhang, Yuhong, et al.
Publicado: (2022)

Circulating MiR-210 and MiR-1246 as Potential Biomarkers for Differentiating Hepatocellular Carcinoma from Metastatic Tumors in the Liver
por: Ahmed, Emad K., et al.
Publicado: (2019)

Circulating miR-106b-3p, miR-101-3p and miR-1246 as diagnostic biomarkers of hepatocellular carcinoma
por: Moshiri, Farzaneh, et al.
Publicado: (2018)

miR-1246 Targets CCNG2 to Enhance Cancer Stemness and Chemoresistance in Oral Carcinomas
por: Lin, Shih-Shen, et al.
Publicado: (2018)

Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4
por: Mo, Li-Jun, et al.
Publicado: (2018)

MIR1246 in body fluids as a biomarker for pancreatic cancer
por: Ishige, Fumitaka, et al.
Publicado: (2020)

Circulating miR-206 and miR-1246 as Markers in the Early Diagnosis of Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease
por: Córdoba-Lanús, Elizabeth, et al.
Publicado: (2023)

Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression
por: Zhang, Wen Cai, et al.
Publicado: (2016)

Identification of serum miR-1246 and miR-150-5p as novel diagnostic biomarkers for high-grade serous ovarian cancer
por: Niemira, Magdalena, et al.
Publicado: (2023)

Detection of miR-1246, miR-23a and miR-451 in sera of colorectal carcinoma patients: a case-control study in Cairo University hospital
por: Salah, Mona, et al.
Publicado: (2020)

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
por: Cooks, Tomer, et al.
Publicado: (2018)

Circulating miR-1246 in the Progression of Chronic Obstructive Pulmonary Disease (COPD) in Patients from the BODE Cohort
por: Cazorla-Rivero, Sara, et al.
Publicado: (2020)

miR‐1246 is implicated as a possible candidate for endometrium remodelling facilitating implantation in buffalo (Bubalus bubalis)
por: Dubey, Pratiksha, et al.
Publicado: (2022)

Circulating miR-1246 and miR-485-3p as Promising Biomarkers of Clinical Response and Outcome in Melanoma Patients Treated with Targeted Therapy
por: Levati, Lauretta, et al.
Publicado: (2022)

miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells
por: Torii, Chisaho, et al.
Publicado: (2021)

MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer
por: Huang, Jing, et al.
Publicado: (2023)

Extracellular vesicles derived from radioresistant oral squamous cell carcinoma cells contribute to the acquisition of radioresistance via the miR‐503‐3p‐BAK axis
por: Yamana, Keisuke, et al.
Publicado: (2021)

5'‑isomiR is the most abundant sequence of miR‑1246, a candidate biomarker of lung cancer, in serum
por: Aiso, Toshiko, et al.
Publicado: (2023)

CADM1 impairs the effect of miR-1246 on promoting cell cycle progression in chemo-resistant leukemia cells
por: Xie, Bei, et al.
Publicado: (2023)

A meta-analysis of the diagnostic value of microRNA-1246 for malignant tumors
por: Xie, Chunlin, et al.
Publicado: (2019)

The roles and diagnostic value of miRNA-1246 in the serum of patients with intracranial aneurysms
por: Jiang, Haijie, et al.
Publicado: (2022)

Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway
por: Peng, Wen, et al.
Publicado: (2019)

lncRNA Mirt2 upregulates miR‐1246 through methylation to suppress LPS‐induced lung cell apoptosis
por: Xu, Xuwen, et al.
Publicado: (2021)

Correlation Analysis of miR-1246 Expression in Saliva of Patients with Chronic Periodontitis and Periodontal Indexes, Inflammatory Cytokines, and Protease Molecules
por: Wu, Shuainan, et al.
Publicado: (2022)

A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3
por: Zhou, You, et al.
Publicado: (2022)

MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth
por: Li, Jingyan, et al.
Publicado: (2021)

ANXA6 Contributes to Radioresistance by Promoting Autophagy via Inhibiting the PI3K/AKT/mTOR Signaling Pathway in Nasopharyngeal Carcinoma
por: Chen, Qianping, et al.
Publicado: (2020)

Downregulation of miR-423-5p Contributes to the Radioresistance in Colorectal Cancer Cells
por: Shang, Yuanyuan, et al.
Publicado: (2021)

miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR
por: Lukosevicius, Rokas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_98so0mie52r0qdbtcnufmlq8hk