RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells

The pocket protein (PP) family consists of the three members RB1, p107 and p130 all possessing tumor suppressive properties. Indeed, the PPs jointly control the G1/S transition mainly by inhibiting E2F transcription factors. Notably, several viral oncoproteins are capable of binding and inhibiting P...

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Detalles Bibliográficos
Autores principales: Hesbacher, Sonja, Pfitzer, Lisa, Wiedorfer, Katharina, Angermeyer, Sabrina, Borst, Andreas, Haferkamp, Sebastian, Scholz, Claus-Jürgen, Wobser, Marion, Schrama, David, Houben, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078066/
https://www.ncbi.nlm.nih.gov/pubmed/27121059
http://dx.doi.org/10.18632/oncotarget.8793

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