Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo

Combination therapy has a higher success rate for many cancers compared to mono-therapy. The treatment of Topotecan (TPT) on gastric cancer (GC) is limited by its toxicity and the potential drug resistance. We found that the combination of the saponin monomer 13 from the dwarf lilyturf tuber (DT-13)...

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Detalles Bibliográficos
Autores principales: Yu, Xiao-Wen, Lin, Sensen, Du, Hong-Zhi, Zhao, Ren-Ping, Feng, Shu-Yun, Yu, Bo-Yang, Zhang, Lu-Yong, Li, Rui-Ming, Qian, Chang-Min, Luo, Xue-Jun, Yuan, Sheng-Tao, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078069/
https://www.ncbi.nlm.nih.gov/pubmed/27105508
http://dx.doi.org/10.18632/oncotarget.8843

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