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Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects

Little is known about the function and phenotype of leukemic stem cells (LSCs) in chronic myeloid leukemia (CML) or about specific markers that discriminate LSCs from normal hematopoietic stem cells (HSCs). CD26 has recently been described as a specific marker of CML LSCs. In the current study, we i...

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Detalles Bibliográficos
Autores principales: Culen, Martin, Borsky, Marek, Nemethova, Veronika, Razga, Filip, Smejkal, Jiri, Jurcek, Tomas, Dvorakova, Dana, Zackova, Daniela, Weinbergerova, Barbora, Semerad, Lukas, Sadovnik, Irina, Eisenwort, Gregor, Herrmann, Harald, Valent, Peter, Mayer, Jiri, Racil, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078071/
https://www.ncbi.nlm.nih.gov/pubmed/27145281
http://dx.doi.org/10.18632/oncotarget.9108