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Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury

Antagonism of CXCR2 receptors, predominately located on neutrophils and critical for their immunomodulatory activity, is an attractive pharmacological therapeutic approach aimed at reducing the potentially damaging effects of heightened neutrophil influx into the lung. The role CXCR2 in lung inflamm...

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Detalles Bibliográficos
Autores principales: Lerner, Chad A., Lei, Wei, Sundar, Isaac K., Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078490/
https://www.ncbi.nlm.nih.gov/pubmed/27826243
http://dx.doi.org/10.3389/fphar.2016.00391