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Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury
Antagonism of CXCR2 receptors, predominately located on neutrophils and critical for their immunomodulatory activity, is an attractive pharmacological therapeutic approach aimed at reducing the potentially damaging effects of heightened neutrophil influx into the lung. The role CXCR2 in lung inflamm...
Autores principales: | Lerner, Chad A., Lei, Wei, Sundar, Isaac K., Rahman, Irfan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078490/ https://www.ncbi.nlm.nih.gov/pubmed/27826243 http://dx.doi.org/10.3389/fphar.2016.00391 |
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