Cargando…

LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer

The proto-oncogene LIM-domain only 2 (lmo2) was traditionally considered to be a pivotal transcriptional regulator in hematopoiesis and leukemia. Recently, the cytosolic localization of LMO2 was revealed in multiple epithelial tissues and a variety of solid tumors. However, the function of LMO2 in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ye, Huang, Di, Wang, Zhaoyang, Wu, Chao, Zhang, Zhao, Wang, Dan, Li, Zongjin, Zhu, Tianhui, Yang, Shuang, Sun, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078767/ https://www.ncbi.nlm.nih.gov/pubmed/27779255 http://dx.doi.org/10.1038/srep36050

Ejemplares similares

LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling
por: Liu, Ye, et al.
Publicado: (2016)

A comprehensive function analysis of LMO2 in different breast cancer subtypes
por: Liu, Ye, et al.
Publicado: (2017)

LMO2 Enhances Lamellipodia/Filopodia Formation in Basal-Type Breast Cancer Cells by Mediating ARP3-Profilin1 Interaction
por: Liu, Ye, et al.
Publicado: (2017)

Biochemical Feature of LMO2 Interactome and LMO2 Function Prospect
por: Wang, Wenhao, et al.
Publicado: (2020)

Ginsenoside Rg3 Inhibits the Growth of Osteosarcoma and Attenuates Metastasis through the Wnt/β-Catenin and EMT Signaling Pathway
por: Mao, Xiaohan, et al.
Publicado: (2020)

Advances of Wnt Signalling Pathway in Colorectal Cancer
por: Zhu, Yaoyao, et al.
Publicado: (2023)

Inhibition of cell proliferation and tumor growth of colorectal cancer by inhibitors of Wnt and Notch signaling pathways
por: Xiao, Yuliang, et al.
Publicado: (2016)

Competitive SPR using an intracellular anti-LMO2 antibody identifies novel LMO2-interacting compounds
por: Canning, Peter, et al.
Publicado: (2021)

ADAMTS12 acts as a cancer promoter in colorectal cancer via activating the Wnt/β-catenin signaling pathway in vitro
por: Li, Chunxue, et al.
Publicado: (2020)

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling
por: Zhang, Junfang, et al.
Publicado: (2013)

LMO1 Plays an Oncogenic Role in Human Glioma Associated With NF-kB Pathway
por: Gao, Lei, et al.
Publicado: (2022)

The role of Wnt signaling pathway in tumor metabolic reprogramming
por: Mo, Yongzhen, et al.
Publicado: (2019)

Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth
por: Ono, Masanori, et al.
Publicado: (2014)

Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4
por: Cubeddu, Liza, et al.
Publicado: (2012)

Crosstalk of the Insulin-Like Growth Factor Receptor with the Wnt Signaling Pathway in Breast Cancer
por: Rota, Lauren M., et al.
Publicado: (2015)

Convergence between Wnt-β-catenin and EGFR signaling in cancer
por: Hu, Tianhui, et al.
Publicado: (2010)

Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma
por: Murphy, N C, et al.
Publicado: (2008)

Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3
por: Lindroos, Josefine, et al.
Publicado: (2013)

T-614 attenuates knee osteoarthritis via regulating Wnt/β-catenin signaling pathway
por: Cong, Shan, et al.
Publicado: (2021)

Circular RNA circLMO7 acts as a microRNA-30a-3p sponge to promote gastric cancer progression via the WNT2/β-catenin pathway
por: Cao, Jiacheng, et al.
Publicado: (2021)

Deletion of the oligopeptide transporter Lmo2193 decreases the virulence of Listeria monocytogenes
por: Li, Honghuan, et al.
Publicado: (2020)

Coordination of LMO7 with FAK Signaling Sustains Epithelial Integrity in Renal Epithelia Exposed to Osmotic Pressure
por: Zhen, Yen-Yi, et al.
Publicado: (2022)

Thymoquinone attenuates tumor growth in Apc(Min) mice by interference with Wnt-signaling
por: Lang, Michaela, et al.
Publicado: (2013)

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways
por: Smith, Stephen, et al.
Publicado: (2014)

An update on Wnt signaling pathway in cancer
por: Zhang, Yanlu, et al.
Publicado: (2020)

Chi and dLMO function antagonistically on Notch signaling through directly regulation of fng transcription
por: Han, Hui, et al.
Publicado: (2016)

Ponatinib Inhibits Multiple Signaling Pathways Involved in STAT3 Signaling and Attenuates Colorectal Tumor Growth
por: Tan, Fiona H., et al.
Publicado: (2018)

Expression Profile and Prognostic Value of Wnt Signaling Pathway Molecules in Colorectal Cancer
por: Wu, Yung-Fu, et al.
Publicado: (2021)

Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells
por: Ma, Li, et al.
Publicado: (2015)

Involvement of SET in the Wnt signaling pathway and the development of human colorectal cancer
por: DONG, LEI, et al.
Publicado: (2014)

Wnt/β-Catenin Signaling Pathway in the Development and Progression of Colorectal Cancer
por: He, Kuang, et al.
Publicado: (2023)

LMO3 downregulation in PCa: A prospective biomarker associated with immune infiltration
por: Xu, Wenchao, et al.
Publicado: (2022)

Associations between LMO1 gene polymorphisms and Wilms' tumor susceptibility
por: Liu, Guo-Chang, et al.
Publicado: (2017)

Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling
por: Shetti, Dattatrya, et al.
Publicado: (2019)

LMO7 as an Unrecognized Factor Promoting Pancreatic Cancer Progression and Metastasis
por: Liu, Xinjian, et al.
Publicado: (2021)

Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma
por: Wang, Weiwei, et al.
Publicado: (2015)

Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway
por: Liu, Yi, et al.
Publicado: (2020)

Lmo4 in the Basolateral Complex of the Amygdala Modulates Fear Learning
por: Maiya, Rajani, et al.
Publicado: (2012)

LMO3 reprograms visceral adipocyte metabolism during obesity
por: Wagner, Gabriel, et al.
Publicado: (2021)

Leptin promotes the growth of breast cancer by upregulating the Wnt/β-catenin pathway
por: Liang, Xi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2fsfbpgpib97i2p2ahgmcab524