Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves

Individuals with a bicuspid aortic valve (BAV) are at significantly higher risk of developing aortic complications than individuals with tricuspid aortic valves (TAV) and defective signaling during the embryonic development and/or life time exposure to abnormal hemodynamic have been proposed as unde...

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Detalles Bibliográficos
Autores principales: Maleki, Shohreh, Kjellqvist, Sanela, Paloschi, Valentina, Magné, Joelle, Branca, Rui Miguel Mamede, Du, Lei, Hultenby, Kjell, Petrini, Johan, Fuxe, Jonas, Lehtiö, Janne, Franco-Cereceda, Anders, Eriksson, Per, Björck, Hanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078843/
https://www.ncbi.nlm.nih.gov/pubmed/27779199
http://dx.doi.org/10.1038/srep35712

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