Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1

Caloric restriction (CR) is known to retard aging and delay functional decline as well as the onset of diseases in most organisms. Ghrelin is secreted from the stomach in response to CR and regulates energy metabolism. We hypothesized that in CR ghrelin has a role in protecting aging-related disease...

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Detalles Bibliográficos
Autores principales: Fujitsuka, N, Asakawa, A, Morinaga, A, Amitani, M S, Amitani, H, Katsuura, G, Sawada, Y, Sudo, Y, Uezono, Y, Mochiki, E, Sakata, I, Sakai, T, Hanazaki, K, Yada, T, Yakabi, K, Sakuma, E, Ueki, T, Niijima, A, Nakagawa, K, Okubo, N, Takeda, H, Asaka, M, Inui, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078860/
https://www.ncbi.nlm.nih.gov/pubmed/26830139
http://dx.doi.org/10.1038/mp.2015.220

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