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Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia

BACKGROUND: Pregnancy toxaemia (PT) is a disease that affects pregnant goats during their last month of gestation and is characterized by a high case fatality rate. This study involved 32 does maintained on a commercial dairy goat farm that were diagnosed with PT. A physical examination was performe...

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Autores principales: Lima, Miguel S., Silveira, Júlia M., Carolino, Nuno, Lamas, Luis P., Pascoal, Rita A., Hjerpe, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078877/
https://www.ncbi.nlm.nih.gov/pubmed/27795825
http://dx.doi.org/10.1186/s13620-016-0075-4
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author Lima, Miguel S.
Silveira, Júlia M.
Carolino, Nuno
Lamas, Luis P.
Pascoal, Rita A.
Hjerpe, Charles A.
author_facet Lima, Miguel S.
Silveira, Júlia M.
Carolino, Nuno
Lamas, Luis P.
Pascoal, Rita A.
Hjerpe, Charles A.
author_sort Lima, Miguel S.
collection PubMed
description BACKGROUND: Pregnancy toxaemia (PT) is a disease that affects pregnant goats during their last month of gestation and is characterized by a high case fatality rate. This study involved 32 does maintained on a commercial dairy goat farm that were diagnosed with PT. A physical examination was performed on and haematology parameters obtained from each doe, at the time of diagnosis. The data from the 24 PT goats that died was compared with the corresponding data from the 8 PT goats that survived. RESULTS: Polypnea, swollen limbs, anorexia with absence of ruminal motility, recumbency, nervous signs and drooping ears were the most frequently observed clinical manifestations. Nineteen out of 21 recumbent goats died. Sixteen out of 17 goats with anorexia and absence of ruminal motility died. Mean beta-hydroxybutyric acid (BHBA) values in the goats that died were not significantly different from those in goats that survived. The blood values for pH and pCO(2) (p < 0.005) as well as for HCO(3) (−), BE and K(+) (p < 0.001) were significantly lower in the goats that died than in those that survived. CONCLUSIONS: The clinical signs most indicative of a poor prognosis are anorexia with absence of ruminal motility and recumbency. Among the blood parameters to be considered, hypokalaemia and metabolic acidosis are the most relevant. Goats with PT have a high mortality and their condition can deteriorate very fast. Based on the authors’s experience, a good strategy to minimize the economic losses caused by PT is to focus on the offspring survival rate since an early decision (induction of kidding or caesarian surgery) can increase the number of alive kids.
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spelling pubmed-50788772016-10-28 Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia Lima, Miguel S. Silveira, Júlia M. Carolino, Nuno Lamas, Luis P. Pascoal, Rita A. Hjerpe, Charles A. Ir Vet J Research BACKGROUND: Pregnancy toxaemia (PT) is a disease that affects pregnant goats during their last month of gestation and is characterized by a high case fatality rate. This study involved 32 does maintained on a commercial dairy goat farm that were diagnosed with PT. A physical examination was performed on and haematology parameters obtained from each doe, at the time of diagnosis. The data from the 24 PT goats that died was compared with the corresponding data from the 8 PT goats that survived. RESULTS: Polypnea, swollen limbs, anorexia with absence of ruminal motility, recumbency, nervous signs and drooping ears were the most frequently observed clinical manifestations. Nineteen out of 21 recumbent goats died. Sixteen out of 17 goats with anorexia and absence of ruminal motility died. Mean beta-hydroxybutyric acid (BHBA) values in the goats that died were not significantly different from those in goats that survived. The blood values for pH and pCO(2) (p < 0.005) as well as for HCO(3) (−), BE and K(+) (p < 0.001) were significantly lower in the goats that died than in those that survived. CONCLUSIONS: The clinical signs most indicative of a poor prognosis are anorexia with absence of ruminal motility and recumbency. Among the blood parameters to be considered, hypokalaemia and metabolic acidosis are the most relevant. Goats with PT have a high mortality and their condition can deteriorate very fast. Based on the authors’s experience, a good strategy to minimize the economic losses caused by PT is to focus on the offspring survival rate since an early decision (induction of kidding or caesarian surgery) can increase the number of alive kids. BioMed Central 2016-10-24 /pmc/articles/PMC5078877/ /pubmed/27795825 http://dx.doi.org/10.1186/s13620-016-0075-4 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Lima, Miguel S.
Silveira, Júlia M.
Carolino, Nuno
Lamas, Luis P.
Pascoal, Rita A.
Hjerpe, Charles A.
Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title_full Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title_fullStr Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title_full_unstemmed Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title_short Usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
title_sort usefulness of clinical observations and blood chemistry values for predicting clinical outcomes in dairy goats with pregnancy toxaemia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078877/
https://www.ncbi.nlm.nih.gov/pubmed/27795825
http://dx.doi.org/10.1186/s13620-016-0075-4
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