Cargando…
Muscle-specific deletion of SOCS3 increases the early inflammatory response but does not affect regeneration after myotoxic injury
BACKGROUND: Muscles of old animals are injured more easily and regenerate poorly, attributed in part to increased levels of circulating pro-inflammatory cytokines. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling cascade is a key mediator of inflammatory cytok...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078888/ https://www.ncbi.nlm.nih.gov/pubmed/27800152 http://dx.doi.org/10.1186/s13395-016-0108-4 |