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Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy

BACKGROUND: Silicosis is characterized by accumulation of fibroblasts and excessive deposition of extracellular matrix. Monocyte chemotactic protein-1-induced protein 1 (MCPIP1) plays a critical role in fibrosis induced by SiO(2). However, the details of the downstream events of MCPIP1 activity in p...

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Detalles Bibliográficos
Autores principales:	Liu, Haijun, Fang, Shencun, Wang, Wei, Cheng, Yusi, Zhang, Yingming, Liao, Hong, Yao, Honghong, Chao, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078901/ https://www.ncbi.nlm.nih.gov/pubmed/27782836 http://dx.doi.org/10.1186/s12989-016-0167-z

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