Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells

BACKGROUND: In order to become functionally competent but harmless mediators of the immune system, T cells undergo a strict educational program in the thymus, where they learn to discriminate between self and non-self. This educational program is, to a large extent, mediated by medullary thymic epit...

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Detalles Bibliográficos
Autores principales: Danan-Gotthold, Miri, Guyon, Clotilde, Giraud, Matthieu, Levanon, Erez Y., Abramson, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078920/
https://www.ncbi.nlm.nih.gov/pubmed/27776542
http://dx.doi.org/10.1186/s13059-016-1079-9

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