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Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report

BACKGROUND: Multifocal choroiditis with panuveitis is a rare disease. The educational merit of this case presentation results from the good documentation and the impressive ocular fundus pictures. CASE PRESENTATION: We illustrate the 3-year course of disease in a 22-year-old myopic white woman with...

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Autores principales: Schroeder, Katharina, Meyer-ter-Vehn, Tobias, Fassnacht-Riederle, Heidi, Guthoff, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078967/
https://www.ncbi.nlm.nih.gov/pubmed/27776541
http://dx.doi.org/10.1186/s13256-016-1069-2
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author Schroeder, Katharina
Meyer-ter-Vehn, Tobias
Fassnacht-Riederle, Heidi
Guthoff, Rainer
author_facet Schroeder, Katharina
Meyer-ter-Vehn, Tobias
Fassnacht-Riederle, Heidi
Guthoff, Rainer
author_sort Schroeder, Katharina
collection PubMed
description BACKGROUND: Multifocal choroiditis with panuveitis is a rare disease. The educational merit of this case presentation results from the good documentation and the impressive ocular fundus pictures. CASE PRESENTATION: We illustrate the 3-year course of disease in a 22-year-old myopic white woman with multifocal choroiditis with panuveitis and secondary choroidal neovascularization. The activity of the disease was evaluated clinically by optical coherence tomography and fluorescein angiography. Choroidal neovascularization was treated by intravitreal bevacizumab (2.5 mg/0.1 ml). Our patient lacked systemic therapy for the first 11 months because of noncompliance. CONCLUSIONS: The case is remarkable as the delayed onset of peripheral lesions and the additional existence of high myopia made diagnosis difficult. In addition, it demonstrates that full outbreak of disease with multiple central and peripheral fundus lesions and secondary choroidal neovascularization can develop without systemic treatment.
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spelling pubmed-50789672016-10-31 Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report Schroeder, Katharina Meyer-ter-Vehn, Tobias Fassnacht-Riederle, Heidi Guthoff, Rainer J Med Case Rep Case Report BACKGROUND: Multifocal choroiditis with panuveitis is a rare disease. The educational merit of this case presentation results from the good documentation and the impressive ocular fundus pictures. CASE PRESENTATION: We illustrate the 3-year course of disease in a 22-year-old myopic white woman with multifocal choroiditis with panuveitis and secondary choroidal neovascularization. The activity of the disease was evaluated clinically by optical coherence tomography and fluorescein angiography. Choroidal neovascularization was treated by intravitreal bevacizumab (2.5 mg/0.1 ml). Our patient lacked systemic therapy for the first 11 months because of noncompliance. CONCLUSIONS: The case is remarkable as the delayed onset of peripheral lesions and the additional existence of high myopia made diagnosis difficult. In addition, it demonstrates that full outbreak of disease with multiple central and peripheral fundus lesions and secondary choroidal neovascularization can develop without systemic treatment. BioMed Central 2016-10-24 /pmc/articles/PMC5078967/ /pubmed/27776541 http://dx.doi.org/10.1186/s13256-016-1069-2 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Schroeder, Katharina
Meyer-ter-Vehn, Tobias
Fassnacht-Riederle, Heidi
Guthoff, Rainer
Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title_full Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title_fullStr Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title_full_unstemmed Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title_short Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
title_sort course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078967/
https://www.ncbi.nlm.nih.gov/pubmed/27776541
http://dx.doi.org/10.1186/s13256-016-1069-2
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