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Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) facilitates fast axonal transport in neurons. However, given that GAPDH does not produce ATP, it is unclear whether glycolysis per se is sufficient to propel vesicles. Although many proteins regulating transport have been identif...

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Detalles Bibliográficos
Autores principales: Hinckelmann, María-Victoria, Virlogeux, Amandine, Niehage, Christian, Poujol, Christel, Choquet, Daniel, Hoflack, Bernard, Zala, Diana, Saudou, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078996/
https://www.ncbi.nlm.nih.gov/pubmed/27775035
http://dx.doi.org/10.1038/ncomms13233