Diversity-oriented synthetic strategy for developing a chemical modulator of protein–protein interaction

Diversity-oriented synthesis (DOS) can provide a collection of diverse and complex drug-like small molecules, which is critical in the development of new chemical probes for biological research of undruggable targets. However, the design and synthesis of small-molecule libraries with improved biolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jonghoon, Jung, Jinjoo, Koo, Jaeyoung, Cho, Wansang, Lee, Won Seok, Kim, Chanwoo, Park, Wonwoo, Park, Seung Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078997/
https://www.ncbi.nlm.nih.gov/pubmed/27774980
http://dx.doi.org/10.1038/ncomms13196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078997/
https://www.ncbi.nlm.nih.gov/pubmed/27774980
http://dx.doi.org/10.1038/ncomms13196

Ejemplares similares