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Diversity-oriented synthetic strategy for developing a chemical modulator of protein–protein interaction

Diversity-oriented synthesis (DOS) can provide a collection of diverse and complex drug-like small molecules, which is critical in the development of new chemical probes for biological research of undruggable targets. However, the design and synthesis of small-molecule libraries with improved biolog...

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Detalles Bibliográficos
Autores principales:	Kim, Jonghoon, Jung, Jinjoo, Koo, Jaeyoung, Cho, Wansang, Lee, Won Seok, Kim, Chanwoo, Park, Wonwoo, Park, Seung Bum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078997/ https://www.ncbi.nlm.nih.gov/pubmed/27774980 http://dx.doi.org/10.1038/ncomms13196

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