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Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy
BACKGROUND: Hydrogen sulfide (H(2)S) is a gasotransmitter that regulates multiple cardiovascular functions. Krüppel‐like factor 5 (KLF5) exerts diverse functions in the cardiovascular system. Whether and how H(2)S regulates KLF5 in myocardial hypertrophy is unknown. METHODS AND RESULTS: In our study...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079055/ https://www.ncbi.nlm.nih.gov/pubmed/27638782 http://dx.doi.org/10.1161/JAHA.116.004160 |