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The Role of Local Ancestry Adjustment in Association Studies Using Admixed Populations
1. For causal variants with similar effect size in all populations, power is generally higher in a study using admixed population than using nonadmixed population, especially for highly differentiated SNPs. This gain of power is achieved with adjustment of global ancestry, which completely removes a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079159/ https://www.ncbi.nlm.nih.gov/pubmed/25043967 http://dx.doi.org/10.1002/gepi.21835 |