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MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
AIMS: Kv7.4, a voltage-dependent potassium channel expressed throughout the vasculature, controls arterial contraction and is compromised in hypertension by an unknown mechanism. MicroRNAs (miRs) are post-transcriptional regulators of protein production and are altered in disease states such as hype...
Autores principales: | Carr, Georgina, Barrese, Vincenzo, Stott, Jennifer B., Povstyan, Oleksandr V., Jepps, Thomas A., Figueiredo, Hericka B., Zheng, Dongling, Jamshidi, Yalda, Greenwood, Iain A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079273/ https://www.ncbi.nlm.nih.gov/pubmed/27389411 http://dx.doi.org/10.1093/cvr/cvw177 |
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