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MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension

AIMS: Kv7.4, a voltage-dependent potassium channel expressed throughout the vasculature, controls arterial contraction and is compromised in hypertension by an unknown mechanism. MicroRNAs (miRs) are post-transcriptional regulators of protein production and are altered in disease states such as hype...

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Detalles Bibliográficos
Autores principales: Carr, Georgina, Barrese, Vincenzo, Stott, Jennifer B., Povstyan, Oleksandr V., Jepps, Thomas A., Figueiredo, Hericka B., Zheng, Dongling, Jamshidi, Yalda, Greenwood, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079273/
https://www.ncbi.nlm.nih.gov/pubmed/27389411
http://dx.doi.org/10.1093/cvr/cvw177

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