Functional Diversity of Cytomegalovirus–Specific T Cells Is Maintained in Older People and Significantly Associated With Protein Specificity and Response Size

Background. Parallel upregulation of several T-cell effector functions (ie, polyfunctionality) is believed to be critical for the protection against viruses but thought to decrease in large T-cell expansions, in particular at older ages. The factors determining T-cell polyfunctionality are incomplet...

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Detalles Bibliográficos
Autores principales: Bajwa, Martha, Vita, Serena, Vescovini, Rosanna, Larsen, Martin, Sansoni, Paolo, Terrazzini, Nadia, Caserta, Stefano, Thomas, David, Davies, Kevin A., Smith, Helen, Kern, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079367/
https://www.ncbi.nlm.nih.gov/pubmed/27521364
http://dx.doi.org/10.1093/infdis/jiw371

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