The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin

The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species...

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Autores principales: Moore, Ondrea A., Gao, Ying, Chen, Allen Y., Brittain, Ross, Chen, Yi Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079443/
https://www.ncbi.nlm.nih.gov/pubmed/27790646
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author Moore, Ondrea A.
Gao, Ying
Chen, Allen Y.
Brittain, Ross
Chen, Yi Charlie
author_facet Moore, Ondrea A.
Gao, Ying
Chen, Allen Y.
Brittain, Ross
Chen, Yi Charlie
author_sort Moore, Ondrea A.
collection PubMed
description The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.
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spelling pubmed-50794432016-10-25 The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin Moore, Ondrea A. Gao, Ying Chen, Allen Y. Brittain, Ross Chen, Yi Charlie J Nutr Med Diet Care Article The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned. 2016-03-22 2016 /pmc/articles/PMC5079443/ /pubmed/27790646 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Moore, Ondrea A.
Gao, Ying
Chen, Allen Y.
Brittain, Ross
Chen, Yi Charlie
The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title_full The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title_fullStr The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title_full_unstemmed The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title_short The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
title_sort extraction, anticancer effect, bioavailability, and nanotechnology of baicalin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079443/
https://www.ncbi.nlm.nih.gov/pubmed/27790646
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