Cargando…

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis

Persistent exposure of the immune system to death cell debris leads to autoantibodies against chromatin in patients with systemic lupus erythematosus (SLE). Deposition of anti-chromatin/chromatin complexes can instigate inflammation in multiple organs including the kidney. Previously we identified s...

Descripción completa

Detalles Bibliográficos
Autores principales: Dieker, Jürgen, Berden, Jo H., Bakker, Marinka, Briand, Jean-Paul, Muller, Sylviane, Voll, Reinhard, Sjöwall, Christopher, Herrmann, Martin, Hilbrands, Luuk B., van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079581/
https://www.ncbi.nlm.nih.gov/pubmed/27780265
http://dx.doi.org/10.1371/journal.pone.0165373