Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells

Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein ubiquitously expressed by Neisseria meningitidis strains and an antigen of the Bexsero(®) vaccine. NHBA binds heparin through a conserved Arg-rich region that is the target of two proteases, the meningococcal NalP and human l...

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Detalles Bibliográficos
Autores principales: Vacca, Irene, Del Tordello, Elena, Gasperini, Gianmarco, Pezzicoli, Alfredo, Di Fede, Martina, Rossi Paccani, Silvia, Marchi, Sara, Mubaiwa, Tsisti D., Hartley-Tassell, Lauren E., Jennings, Michael P., Seib, Kate L., Masignani, Vega, Pizza, Mariagrazia, Serruto, Davide, Aricò, Beatrice, Delany, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079597/
https://www.ncbi.nlm.nih.gov/pubmed/27780200
http://dx.doi.org/10.1371/journal.pone.0162878

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