Cargando…

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial

OBJECTIVE: To identify genetic determinants of increased cardiovascular mortality among subjects with type 2 diabetes who underwent intensive glycemic therapy in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. RESEARCH DESIGN AND METHODS: A total of 6.8 million common variants...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shah, Hetal S., Gao, He, Morieri, Mario Luca, Skupien, Jan, Marvel, Skylar, Paré, Guillaume, Mannino, Gaia C., Buranasupkajorn, Patinut, Mendonca, Christine, Hastings, Timothy, Marcovina, Santica M., Sigal, Ronald J., Gerstein, Hertzel C., Wagner, Michael J., Motsinger-Reif, Alison A., Buse, John B., Kraft, Peter, Mychaleckyj, Josyf C., Doria, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Emerging Science, Concepts, and Approach to Precision Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079609/ https://www.ncbi.nlm.nih.gov/pubmed/27527847 http://dx.doi.org/10.2337/dc16-0285

Ejemplares similares

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial
por: Morieri, Mario Luca, et al.
Publicado: (2018)

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD
por: Shah, Hetal S., et al.
Publicado: (2018)

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid
por: Morieri, Mario Luca, et al.
Publicado: (2020)

The Impact of Precision Medicine in Diabetes: A Multidimensional Perspective
por: Rich, Stephen S., et al.
Publicado: (2016)

ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
por: Fleming, Jonathon, et al.
Publicado: (2021)

Buffy coat specimens remain viable as a DNA source for highly multiplexed genome-wide genetic tests after long term storage
por: Mychaleckyj, Josyf C, et al.
Publicado: (2011)

ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
por: Fleming, Jonathon, et al.
Publicado: (2022)

Reversibility of Fenofibrate Therapy–Induced Renal Function Impairment in ACCORD Type 2 Diabetic Participants
por: Mychaleckyj, Josyf C., et al.
Publicado: (2012)

Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial
por: Marvel, Skylar W., et al.
Publicado: (2017)

Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response
por: Graham, Hillary T., et al.
Publicado: (2016)

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies
por: Tang, Yaling, et al.
Publicado: (2019)

Hypokalemic Periodic Paralysis as the First Manifestation of Thyrotropin-Secreting Pituitary Adenoma
por: Kaewkrasaesin, Chatchon, et al.
Publicado: (2019)

Membrane Microreactors for the On‐Demand Generation, Separation, and Reaction of Gases
por: Hone, Christopher A., et al.
Publicado: (2020)

Synthetic Approaches to Break the Chemical Shift Degeneracy of Glycans
por: Dal Colle, Marlene C. S., et al.
Publicado: (2022)

Managing alcohol-related attendances in emergency care: can diversion to bespoke services lessen the burden?
por: Irving, Andy, et al.
Publicado: (2018)

From Hippocrates to HIPAA: Privacy and confidentiality in Emergency Medicine—Part II: Challenges in the emergency department
por: Moskop, John C., et al.
Publicado: (2005)

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes
por: Prudente, Sabrina, et al.
Publicado: (2015)

Synergism Between Circulating Tumor Necrosis Factor Receptor 2 and HbA(1c) in Determining Renal Decline During 5–18 Years of Follow-up in Patients With Type 1 Diabetes and Proteinuria
por: Skupien, Jan, et al.
Publicado: (2014)

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning
por: Marvel, Skylar W., et al.
Publicado: (2020)

Clinical characteristics and treatment outcomes in acromegaly, a retrospective single-center case series from Thailand
por: Ganokroj, Poranee, et al.
Publicado: (2021)

Family-Based Association Analysis Confirms the Role of the Chromosome 9q21.32 Locus in the Susceptibility of Diabetic Nephropathy
por: Pezzolesi, Marcus G., et al.
Publicado: (2013)

38081 A Whole Blood Signature of Neutrophil Expression and Adaptive Immune Downregulation Characterizes Sepsis Mortality
por: Giannini, H.M., et al.
Publicado: (2021)

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning
por: Marvel, Skylar W., et al.
Publicado: (2021)

4167 Peri-transplant Lung Microbiome Reveal Oral Bacteria, Pepsin And Inflammatory Markers Co-associate With Primary Graft Dysfunction, Implicating Aspiration As A Potential Contributor
por: McGinniss, John Evan, et al.
Publicado: (2020)

Generalist Genes: Genetic Links Between Brain, Mind, and Education
por: Plomin, Robert, et al.
Publicado: (2007)

Thermodynamics and Kinetics of Prenucleation Clusters, Classical and Non-Classical Nucleation
por: Zahn, Dirk
Publicado: (2015)

Bioisosteric Matrices for Ligands of Serotonin Receptors
por: Warszycki, Dawid, et al.
Publicado: (2015)

Gold Carbene or Carbenoid: Is There a Difference?
por: Wang, Yahui, et al.
Publicado: (2015)

Dynamic Covalent Nanoparticle Building Blocks
por: Kay, Euan R.
Publicado: (2016)

N‐Phosphine Oxide‐Substituted Imidazolylidenes (PoxIms): Multifunctional Multipurpose Carbenes
por: Hazra, Sunit, et al.
Publicado: (2017)

Cooperative Surface‐Particle Catalysis: The Role of the “Active Doughnut” in Catalytic Oxidation
por: Slot, Thierry K., et al.
Publicado: (2018)

Nitrene Radical Intermediates in Catalytic Synthesis
por: Kuijpers, Petrus F., et al.
Publicado: (2017)

Fine Structure in Electronic Spectra of Cyanine Dyes: Are Sub‐Bands Largely Determined by a Dominant Vibration or a Collection of Singly Excited Vibrations?
por: Mustroph, Heinz, et al.
Publicado: (2018)

9‐Membered Carbocycles: Strategies and Tactics for their Synthesis
por: Huber, Tatjana, et al.
Publicado: (2018)

Selection, Addiction and Catalysis: Emerging Trends for the Incorporation of Noncanonical Amino Acids into Peptides and Proteins in Vivo
por: Mayer, Clemens
Publicado: (2019)

Amine–Borane Dehydropolymerization: Challenges and Opportunities
por: Colebatch, Annie L., et al.
Publicado: (2018)

Air Pollution in Europe
por: Koolen, Cedric D., et al.
Publicado: (2018)

Soft Crystals: Flexible Response Systems with High Structural Order
por: Kato, Masako, et al.
Publicado: (2019)

Ferroelectric Oxides for Solar Energy Conversion, Multi‐Source Energy Harvesting/Sensing, and Opto‐Ferroelectric Applications
por: Bai, Yang, et al.
Publicado: (2019)

Future Challenges in Heterogeneous Catalysis: Understanding Catalysts under Dynamic Reaction Conditions
por: Kalz, Kai F., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mkpj9h10l5d3j2r2rd2o3abpgi