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F(1)F(0) ATP Synthase–Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline
Mitochondrial abnormalities are well known to cause cognitive decline. However, the underlying molecular basis of mitochondria-associated neuronal and synaptic dysfunction in the diabetic brain remains unclear. Here, using a mitochondrial single-channel patch clamp and cyclophilin D (CypD)-deficient...
Autores principales: | Yan, Shijun, Du, Fang, Wu, Long, Zhang, Zhihua, Zhong, Changjia, Yu, Qing, Wang, Yongfu, Lue, Lih-Fen, Walker, Douglas G., Douglas, Justin T., Yan, Shirley ShiDu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079631/ https://www.ncbi.nlm.nih.gov/pubmed/27554467 http://dx.doi.org/10.2337/db16-0556 |
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