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Glycemic Control with Ipragliflozin, a Novel Selective SGLT2 Inhibitor, Ameliorated Endothelial Dysfunction in Streptozotocin-Induced Diabetic Mouse

BACKGROUND: Endothelial dysfunction caused by increased oxidative stress is a critical initiator of macro- and micro-vascular disease development in diabetic patients. Ipragliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, offers a novel approach for the treatment of diabetes b...

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Detalles Bibliográficos
Autores principales: Salim, Hotimah Masdan, Fukuda, Daiju, Yagi, Shusuke, Soeki, Takeshi, Shimabukuro, Michio, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080286/
https://www.ncbi.nlm.nih.gov/pubmed/27833913
http://dx.doi.org/10.3389/fcvm.2016.00043