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Glycemic Control with Ipragliflozin, a Novel Selective SGLT2 Inhibitor, Ameliorated Endothelial Dysfunction in Streptozotocin-Induced Diabetic Mouse
BACKGROUND: Endothelial dysfunction caused by increased oxidative stress is a critical initiator of macro- and micro-vascular disease development in diabetic patients. Ipragliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, offers a novel approach for the treatment of diabetes b...
Autores principales: | Salim, Hotimah Masdan, Fukuda, Daiju, Yagi, Shusuke, Soeki, Takeshi, Shimabukuro, Michio, Sata, Masataka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080286/ https://www.ncbi.nlm.nih.gov/pubmed/27833913 http://dx.doi.org/10.3389/fcvm.2016.00043 |
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