The Andes Virus Nucleocapsid Protein Directs Basal Endothelial Cell Permeability by Activating RhoA

Andes virus (ANDV) predominantly infects microvascular endothelial cells (MECs) and nonlytically causes an acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). In HPS patients, virtually every pulmonary MEC is infected, MECs are enlarged, and infection results in vascular leakage and hi...

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Detalles Bibliográficos
Autores principales: Gorbunova, Elena E., Simons, Matthew J., Gavrilovskaya, Irina N., Mackow, Erich R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080385/
https://www.ncbi.nlm.nih.gov/pubmed/27795403
http://dx.doi.org/10.1128/mBio.01747-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080385/
https://www.ncbi.nlm.nih.gov/pubmed/27795403
http://dx.doi.org/10.1128/mBio.01747-16

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