Mitochondrial function controls intestinal epithelial stemness and proliferation

Control of intestinal epithelial stemness is crucial for tissue homeostasis. Disturbances in epithelial function are implicated in inflammatory and neoplastic diseases of the gastrointestinal tract. Here we report that mitochondrial function plays a critical role in maintaining intestinal stemness a...

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Detalles Bibliográficos
Autores principales: Berger, Emanuel, Rath, Eva, Yuan, Detian, Waldschmitt, Nadine, Khaloian, Sevana, Allgäuer, Michael, Staszewski, Ori, Lobner, Elena M., Schöttl, Theresa, Giesbertz, Pieter, Coleman, Olivia I., Prinz, Marco, Weber, Achim, Gerhard, Markus, Klingenspor, Martin, Janssen, Klaus-Peter, Heikenwalder, Mathias, Haller, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080445/
https://www.ncbi.nlm.nih.gov/pubmed/27786175
http://dx.doi.org/10.1038/ncomms13171

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