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Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice

The rupture and erosion of atherosclerotic plaque can induce coronary thrombosis. Prolyl-4-hydroxylase (P4H) plays a central role in the synthesis of all known types of collagens, which are the most abundant constituent of the extracellular matrix in atherosclerotic plaque. The pathogenesis of ather...

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Detalles Bibliográficos
Autores principales:	Cao, Xiao-qing, Liu, Xin-xin, Li, Meng-meng, Zhang, Yu, Chen, Liang, Wang, Lin, Di, Ming-xue, Zhang, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080484/ https://www.ncbi.nlm.nih.gov/pubmed/27818566 http://dx.doi.org/10.1155/2016/1701637

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