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Effect of Culture Condition Variables on Human Endostatin Gene Expression in Escherichia coli Using Response Surface Methodology

BACKGROUND: Recombinant human endostatin (rhES) is an angiogenesis inhibitor used as a specific drug for the treatment of non-small-cell lung cancer. As mRNA concentration affects the recombinant protein expression level, any factor affecting mRNA concentration can alter the protein expression level...

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Detalles Bibliográficos
Autores principales:	Mohajeri, Abbas, Pilehvar-Soltanahmadi, Yones, Abdolalizadeh, Jalal, Karimi, Pouran, Zarghami, Nosratollah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Kowsar 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080621/ https://www.ncbi.nlm.nih.gov/pubmed/27800134 http://dx.doi.org/10.5812/jjm.34091

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