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Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma

Lung cancer is the number one cause of cancer-related deaths worldwide. DNA methylation is an epigenetic mechanism that regulates gene expression, and disease-specific methylation changes can be targeted as biomarkers. We have compared the genome-wide methylation pattern in tumor and tumor-adjacent...

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Detalles Bibliográficos
Autores principales: Daugaard, Iben, Dominguez, Diana, Kjeldsen, Tina E., Kristensen, Lasse S., Hager, Henrik, Wojdacz, Tomasz K., Hansen, Lise Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080630/
https://www.ncbi.nlm.nih.gov/pubmed/27782156
http://dx.doi.org/10.1038/srep35807