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Does upregulated host cell receptor expression provide a link between bacterial adhesion and chronic respiratory disease?

Expression of the platelet-activating factor receptor is upregulated in the respiratory epithelium of smokers and chronic obstructive pulmonary disease patients. We have recently determined that increased expression of PAFr correlates with higher levels of adhesion to human bronchial epithelial cell...

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Detalles Bibliográficos
Autores principales: O’Toole, Ronan F., Shukla, Shakti D., Walters, Eugene H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080759/
https://www.ncbi.nlm.nih.gov/pubmed/27782846
http://dx.doi.org/10.1186/s12967-016-1063-x