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Angiopoietin-2 impairs collateral artery growth associated with the suppression of the infiltration of macrophages in mouse hindlimb ischaemia

BACKGROUND: Angiopoietin-2 (Ang-2), a ligand of the Tie-2 receptor, plays an important role in maintaining endothelial cells and in destabilizing blood vessels. Collateral artery growth (arteriogenesis) is a key adaptive response to arterial occlusion. It is unknown whether the destabilization of bl...

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Detalles Bibliográficos
Autores principales:	Tan, Xiaoyong, Yan, Kai, Ren, Meiping, Chen, Ni, Li, Yongjie, Deng, Xin, Wang, Liqun, Li, Rong, Luo, Mao, Liu, Yong, Liu, Yan, Wu, Jianbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080762/ https://www.ncbi.nlm.nih.gov/pubmed/27784306 http://dx.doi.org/10.1186/s12967-016-1055-x

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