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Aqueous extract of Lithospermi radix attenuates oxaliplatin-induced neurotoxicity in both in vitro and in vivo models

BACKGROUND: Oxaliplatin can induce peripheral neuropathy (OXIPN) as an adverse side effect in cancer patients. Until now, no effective preventive or therapeutic drug has been developed; therefore, the dose-limiting factor of OXIPN is still an obstacle in the use of oxaliplatin to treat cancer patien...

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Detalles Bibliográficos
Autores principales: Cho, Eun-Sang, Yi, Jin-Mu, Park, Jong-Shik, Lee, You Jin, Lim, Chae Jun, Bang, Ok-Sun, Kim, No Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080763/
https://www.ncbi.nlm.nih.gov/pubmed/27782842
http://dx.doi.org/10.1186/s12906-016-1396-2

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