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Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

BACKGROUND: In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood. The aim of this study was to analyze the immunosu...

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Detalles Bibliográficos
Autores principales: de Lourdes Mora-García, María, García-Rocha, Rosario, Morales-Ramírez, Omar, Montesinos, Juan José, Weiss-Steider, Benny, Hernández-Montes, Jorge, Ávila-Ibarra, Luis Roberto, Don-López, Christian Azucena, Velasco-Velázquez, Marco Antonio, Gutiérrez-Serrano, Vianey, Monroy-García, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080842/
https://www.ncbi.nlm.nih.gov/pubmed/27782859
http://dx.doi.org/10.1186/s12967-016-1057-8