Cargando…

Combined Toxic Effects of Polar and Nonpolar Chemicals on Human Hepatocytes (HepG2) Cells by Quantitative Property-Activity Relationship Modeling

We determined the toxicity of mixtures of ethyl acetate (EA), isopropyl alcohol (IPA), methyl ethyl ketone (MEK), toluene (TOL) and xylene (XYL) with half-maximal effective concentration (EC(50)) values obtained using human hepatocytes cells. According to these data, quantitative property-activity r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ki-Woong, Won, Yong Lim, Park, Dong Jin, Kim, Young Sun, Jin, Eun Sil, Lee, Sung Kwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Toxicology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080860/ https://www.ncbi.nlm.nih.gov/pubmed/27818736 http://dx.doi.org/10.5487/TR.2016.32.4.337

Ejemplares similares

Differential Inhibite Effect of Xanthohumol on HepG2 Cells and Primary Hepatocytes
por: Zhang, Xiuli, et al.
Publicado: (2022)

Data on the expression of PEPCK in HepG2 hepatocytes transfected with miR-195
por: Yang, Won-Mo, et al.
Publicado: (2017)

E-Cigarette Flavoring Chemicals Induce Cytotoxicity in HepG2 Cells
por: Rickard, Brittany P., et al.
Publicado: (2021)

Glucose availability determines silver nanoparticles toxicity in HepG2
por: Zuberek, Mariusz, et al.
Publicado: (2015)

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
por: Grünig, David, et al.
Publicado: (2018)

Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells
por: Go, Hiroe, et al.
Publicado: (2015)

Inhibitory Effect of Gardenoside on Free Fatty Acid-Induced Steatosis in HepG2 Hepatocytes
por: Liang, Huiqing, et al.
Publicado: (2015)

Data on the decreased expression of FOXO1 by miR-1271 in HepG2 hepatocytes
por: Yang, Won-Mo, et al.
Publicado: (2017)

Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells
por: Franko, Andras, et al.
Publicado: (2019)

Toxicity Assessment of Octachlorostyrene in Human Liver Carcinoma (HepG2) Cells
por: Ren, Guofa, et al.
Publicado: (2022)

β-Adrenergic Agonist and Antagonist Regulation of Autophagy in HepG2 Cells, Primary Mouse Hepatocytes, and Mouse Liver
por: Farah, Benjamin L., et al.
Publicado: (2014)

Resveratrol metabolites ameliorate insulin resistance in HepG2 hepatocytes by modulating IRS-1/AMPK
por: Teng, Wendi, et al.
Publicado: (2018)

Response differences of HepG2 and Primary Mouse Hepatocytes to morphological changes in electrospun PCL scaffolds
por: Bate, Thomas S. R., et al.
Publicado: (2021)

Tebuconazole Fungicide Induces Lipid Accumulation and Oxidative Stress in HepG2 Cells
por: Kwon, Hyuk-Cheol, et al.
Publicado: (2021)

The p90rsk-mediated signaling of ethanol-induced cell proliferation in HepG2 cell line
por: Kim, Han Sang, et al.
Publicado: (2016)

Polar or nonpolar? That is not the question for perovskite solar cells
por: Huang, Boyuan, et al.
Publicado: (2021)

Acute and subchronic toxicity study of nonpolar extract of licorice roots in mice
por: Kim, Hyun‐Yong, et al.
Publicado: (2020)

Ablation of SMUG1 Reduces Cell Viability and Increases UVC-Mediated Apoptosis in Hepatocarcinoma HepG2 Cells
por: An, Mi-Jin, et al.
Publicado: (2021)

NMR-based Metabolomic Techniques Identify the Toxicity of Emodin in HepG2 Cells
por: Chen, Chang, et al.
Publicado: (2018)

Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
por: Korga, Agnieszka, et al.
Publicado: (2019)

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells
por: Lee, Seung-Cheol, et al.
Publicado: (2021)

Involvement of hepatocyte growth factor in increased integrin expression on HepG2 cells triggered by adhesion to endothelial cells.
por: Kawakami-Kimura, N., et al.
Publicado: (1997)

HCMV Activates the IL-6-JAK-STAT3 Axis in HepG2 Cells and Primary Human Hepatocytes
por: Lepiller, Quentin, et al.
Publicado: (2013)

Dual Effects of Ketoconazole cis-Enantiomers on CYP3A4 in Human Hepatocytes and HepG2 Cells
por: Novotná, Aneta, et al.
Publicado: (2014)

Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells
por: Ramirez, Tzutzuy, et al.
Publicado: (2017)

Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model
por: Elje, Elisabeth, et al.
Publicado: (2020)

The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity
por: Lőrincz, Tamás, et al.
Publicado: (2021)

Molecular Mechanisms behind Safranal’s Toxicity to HepG2 Cells from Dual Omics
por: Nelson, David Roy, et al.
Publicado: (2022)

Role of biotransformation in the diazinon-induced toxicity in HepG2 cells and antioxidant protection by tetrahydrocurcumin
por: Miranda, Camila Araújo, et al.
Publicado: (2022)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Polarized Versus Nonpolarized Dermoscopy for Hair and Scalp Evaluation
por: Kaliyadan, Feroze
Publicado: (2016)

Hexavalent chromium induces apoptosis in human liver (HepG2) cells via redox imbalance
por: Das, Joydeep, et al.
Publicado: (2015)

Comparison of different polar compounds-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells
por: Li, Jinwei, et al.
Publicado: (2016)

Influence of total polar compounds on lipid metabolism, oxidative stress and cytotoxicity in HepG2 cells
por: Ju, Jingjie, et al.
Publicado: (2019)

Anti-lipoapoptotic effect of Artemisia capillaris extract on free fatty acids-induced HepG2 cells
por: Jang, Eungyeong, et al.
Publicado: (2014)

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model
por: Park, Jae-Yeo, et al.
Publicado: (2015)

Chemical Constituent Profiling of Phyllostachys heterocycla var. Pubescens with Selective Cytotoxic Polar Fraction through EGFR Inhibition in HepG2 Cells
por: Abdelhameed, Reda F. A., et al.
Publicado: (2021)

Effects of Amino Acids Supplementation on Lipid and Glucose Metabolism in HepG2 Cells
por: Wang, Shuang, et al.
Publicado: (2022)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_suj5sngdadr9a1uf9jih8ishti