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Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue

A method for the molecular mapping of formalin-fixed, paraffin-embedded human hippocampal tissue affected by Alzheimer's disease (AD) is presented. This approach utilizes imaging mass spectrometry (IMS) with matrix-assisted laser desorption/ionization (MALDI). The usefulness of this technique i...

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Detalles Bibliográficos
Autores principales: Kelley, Andrea R., Perry, George, Bethea, Chloe, Castellani, Rudolph J., Bach, Stephan B.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080873/
https://www.ncbi.nlm.nih.gov/pubmed/27843502
http://dx.doi.org/10.2174/1874205X01610010088