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PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas

BACKGROUND & OBJECTIVES: Despite their high occurrence and associated significant level of morbidity manifesting as spectrum of clinical symptoms, the pathogenesis of uterine leiomyomas (ULs) remains unclear. We investigated expression profile of tumour suppressor genes PTEN (phosphatase and ten...

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Detalles Bibliográficos
Autores principales: Makker, Annu, Goel, Madhu Mati, Mahdi, Abbas Ali, Bhatia, Vikram, Das, Vinita, Agarwal, Anjoo, Pandey, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080920/
https://www.ncbi.nlm.nih.gov/pubmed/27748285
http://dx.doi.org/10.4103/0971-5916.191808