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Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione

Humanin (HN) is a small mitochondrial-encoded peptide with neuroprotective properties. We have recently shown protection of retinal pigmented epithelium (RPE) cells by HN in oxidative stress; however, the effect of HN on endoplasmic reticulum (ER) stress has not been evaluated in any cell type. Our...

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Detalles Bibliográficos
Autores principales:	Matsunaga, Douglas, Sreekumar, Parameswaran G., Ishikawa, Keijiro, Terasaki, Hiroto, Barron, Ernesto, Cohen, Pinchas, Kannan, Ram, Hinton, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081188/ https://www.ncbi.nlm.nih.gov/pubmed/27783653 http://dx.doi.org/10.1371/journal.pone.0165150

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