Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis

BACKGROUND: The Hedgehog (HH) pathway is a mediator in pancreatic ductal adenocarcinoma (PDAC). Surprisingly, previous studies suggested that primary cilia (PC), the essential organelles for HH signal transduction, were lost in PDAC. The aim of this study was to determine the presence of PC in human...

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Detalles Bibliográficos
Autores principales: Schimmack, Simon, Kneller, Sarah, Dadabaeva, Nigora, Bergmann, Frank, Taylor, Andrew, Hackert, Thilo, Werner, Jens, Strobel, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081192/
https://www.ncbi.nlm.nih.gov/pubmed/27783689
http://dx.doi.org/10.1371/journal.pone.0164231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081192/
https://www.ncbi.nlm.nih.gov/pubmed/27783689
http://dx.doi.org/10.1371/journal.pone.0164231

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