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Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis
BACKGROUND: The Hedgehog (HH) pathway is a mediator in pancreatic ductal adenocarcinoma (PDAC). Surprisingly, previous studies suggested that primary cilia (PC), the essential organelles for HH signal transduction, were lost in PDAC. The aim of this study was to determine the presence of PC in human...
Autores principales: | Schimmack, Simon, Kneller, Sarah, Dadabaeva, Nigora, Bergmann, Frank, Taylor, Andrew, Hackert, Thilo, Werner, Jens, Strobel, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081192/ https://www.ncbi.nlm.nih.gov/pubmed/27783689 http://dx.doi.org/10.1371/journal.pone.0164231 |
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