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MicroRNA-16 Alleviates Inflammatory Pain by Targeting Ras-Related Protein 23 (RAB23) and Inhibiting p38 MAPK Activation

BACKGROUND: The purpose of our study was to determine the functional role of microRNA (miR)-16 in chronic inflammatory pain and to disclose its underlying molecular mechanism. MATERIAL/METHODS: Inflammatory pain was induced by injection of complete Freund’s adjuvant (CFA) to Wistar rats. The pWPXL-m...

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Detalles Bibliográficos
Autores principales: Chen, Wenjin, Guo, Shengdong, Wang, Shenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081236/
https://www.ncbi.nlm.nih.gov/pubmed/27770129
http://dx.doi.org/10.12659/MSM.897580