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Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis

BACKGROUND: Dose-related toxicity is the major restriction of cisplatin and cisplatin-combination chemotherapy, and is a challenge for advanced gastric cancer treatment. We explored the possibility of using Paris saponin I as an agent to sensitize gastric cancer cells to cisplatin, and examined the...

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Detalles Bibliográficos
Autores principales: Song, Shuichuan, Du, Leiwen, Jiang, Hao, Zhu, Xinhai, Li, Jinhui, Xu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081239/
https://www.ncbi.nlm.nih.gov/pubmed/27755523
http://dx.doi.org/10.12659/MSM.898232